TWO NEW BISNORDITERPENOID ALKALOIDS SINOMONTANINES D AND E FROM ACONITUM SINOMONTANUM

AIM: To study the alkaloids from the roots of Aconitum sinomontanum of Ranunculaceae. METHODS: The alkaloids were isolated using silica gel chromatography (column and chromatodron), and the structures were elucidated on the basis of IR, MS, ¹HNMR, ¹³CNMR, ¹H-¹H COSY, HMQC and HMBC analysis. RESULTS: Twenty seven compounds have been isolated from the total alkaloids, two of which are sinomontanines D (1) and E (2). CONCLUSION: Sinomontanines D (1) and E (2) are new bisnorditerpenoid alkaloids.