YAN Min, ZHANG Zhen, LEI Xing-Han, XI Yu-Rui , XU Yu-Xin, . STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVESJ. Acta Pharmaceutica Sinica, 1985, 20(3): 219-223.
Citation: YAN Min, ZHANG Zhen, LEI Xing-Han, XI Yu-Rui , XU Yu-Xin, . STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVESJ. Acta Pharmaceutica Sinica, 1985, 20(3): 219-223.
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STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVES

    Abstract
  • In order to improve the clinical efficacy of the new oral filaricide, Furapyrimidone, a number of 5-nitro-2-thienylazomethine and 3,5-dinitro-2-thicnylamine derivatives were synthesized. After screening, twenty-one out of thirty-two compounds were found to possess pronounced macrofilaricidal effect.
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