PY Ding, XX Zhu, MS Cai , DQ Yu, . STUDIES ON SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF CIMICIFUGAMIDE FROM CIMICIFUGA DAHURICA, AND ITS ANALOGUESJ. Acta Pharmaceutica Sinica, 1997, 32(10): 755-760.
Citation:
PY Ding, XX Zhu, MS Cai , DQ Yu, . STUDIES ON SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF CIMICIFUGAMIDE FROM CIMICIFUGA DAHURICA, AND ITS ANALOGUESJ. Acta Pharmaceutica Sinica, 1997, 32(10): 755-760.
PY Ding, XX Zhu, MS Cai , DQ Yu, . STUDIES ON SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF CIMICIFUGAMIDE FROM CIMICIFUGA DAHURICA, AND ITS ANALOGUESJ. Acta Pharmaceutica Sinica, 1997, 32(10): 755-760.
Citation:
PY Ding, XX Zhu, MS Cai , DQ Yu, . STUDIES ON SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF CIMICIFUGAMIDE FROM CIMICIFUGA DAHURICA, AND ITS ANALOGUESJ. Acta Pharmaceutica Sinica, 1997, 32(10): 755-760.
STUDIES ON SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF CIMICIFUGAMIDE FROM CIMICIFUGA DAHURICA, AND ITS ANALOGUES
Cimicifuga dahurica, was accomplished by a reaction sequence of seven steps in an overall yield of 31%. Trifluoroacetoxy was used as leaving group at the anomeric carbon. The target product was characterized by IR, MS,1HNMR, 13CNMR and elemental analysis. In addition, seven analogues were synthesized and their preliminary pharmacological activities were tested.
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