DETERMINATION OF SALBUTAMOL IN HUMAN URINE

X Liu, YZ Zhang, CJ Zhang , L Ye, . DETERMINATION OF SALBUTAMOL IN HUMAN URINEJ. Acta Pharmaceutica Sinica, 1994, 29(6): 454-458.

Citation:

X Liu, YZ Zhang, CJ Zhang , L Ye, . DETERMINATION OF SALBUTAMOL IN HUMAN URINEJ. Acta Pharmaceutica Sinica, 1994, 29(6): 454-458.

Citation:

X Liu, YZ Zhang, CJ Zhang , L Ye, . DETERMINATION OF SALBUTAMOL IN HUMAN URINEJ. Acta Pharmaceutica Sinica, 1994, 29(6): 454-458.

Abstract

Salbutamol(2.4 mg)was administrated to a healthy male．The urine was analysed by GC—MS．95% of the drug was excreted in 24 h in unconjugated form．The pH of urine was shown to strongly affect the extraction rate，good recovery was obtained at pH 8.8．With this method，salbutamol can be determined simply，quickly and accurately．

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