APPLICATION OF 2D-NMR TECHNIQUES IN THE STRUC TURE DETERMINATION OF HYPODEMATINE
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Abstract
A novel alkaloid, named hypodematine, was isolated from Hypodematium sinense Iwatsuki (belonging to the lypterdaceae ). Its structure has been elucidated to have a novel skeleton of benzo-aza-cyclooctatetraene with a phenyl substitution by means of the 1H-1H COSY, 1H-13C COSY and long-range 1H-13C COSY spectroscopy.
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