L Xie, H Chi , TH Zhou, . SEPARATION OF EPIMERS OF ANISODAMINE (654-2) WITH HPLC USING CHIRAL ADDITIVES IN THE MOBILE PHASEJ. Acta Pharmaceutica Sinica, 1991, 26(7): 527-530.
Citation: L Xie, H Chi , TH Zhou, . SEPARATION OF EPIMERS OF ANISODAMINE (654-2) WITH HPLC USING CHIRAL ADDITIVES IN THE MOBILE PHASEJ. Acta Pharmaceutica Sinica, 1991, 26(7): 527-530.
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SEPARATION OF EPIMERS OF ANISODAMINE (654-2) WITH HPLC USING CHIRAL ADDITIVES IN THE MOBILE PHASE

    Abstract
  • The separation of epimers of anisodamine were studied with HPLC using a reversed phase ODS C18 column. Several chiral additives were tried in the mobile phases.d-Camphorsulfonic acid and L- (+)-dibutyl tartrate showed good resolution ability for the separation of the isomers, a pair of epimers of anisodamine were well separated; while β-cyclodextrin appeared to have no selectivity for the epimers.
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