STUDIES ON THE FLAVONOIDS PRESENT IN CHINESE DRUGS Ⅺ. THE CHEMICAL COMPOSITION OF THE ROOT BARK OF DAPHNE GENKWA SIEB. ET ZUCC.

The root bark of Daphne genkwa Sieb. et Zucc. (Thymelaeceae) has been used as remedy for ascites of the late stage schistosomoiasis. Three crystalline substances have been isolated as follows: (1) The first, mp. 135℃, has been identified as ,β-sitosterol. (2) The second, C₂₇H₃₀O₁₄ (0.09%), possesses double melting points 186℃ and 270℃.From the studies of its chemical and physical properties, it is proved to be a new flavone glycoside, genkwanin-5-glucoxyloside or genkwanin-5-xyloglucoside, and is named Yuenkanin. (3) The third is a phenolic compound, C₁₅H₁₄O₆ (0.04%), mp. 192℃,which possesses the activity of fish poisoning and coronary vasodilation.