STUDY ON THE ABSORBED COMPONENTS IN SERUM AFTER ORAL ADMINISTRATION OF GINSENOSIDE Rb₁ IN RATS

AIM: The experiment was carried out in rats to study the real active component in serum after oral administration of G-Rb₁ 500 mg·kg^-1. METHODS: The metabolites in serum and urine samples were detected using electron spurt ion mass spectroscopy(ESI-MS). RESULTS: Metabolites with molecular weight 1108, 946 and 784 (amu) were shown to be corresponding to Rb₁, Rd and F₂, respectively. CONCLUSION: Rb₁ and its metabolites Rd and F₂ were absorbed into serum after oral administration of Rb₁.