ZHANG Hong-qing, LIU Hui-tu, DENG Zao-xi, PAN Wei-lin, HU Yun-ying , XUE Shao-bai, . CELL CYCLE PHASE SENSITIVITY OF CHO CELL TO PINGYANGMYCINJ. Acta Pharmaceutica Sinica, 1982, 17(10): 755-760.
Citation: ZHANG Hong-qing, LIU Hui-tu, DENG Zao-xi, PAN Wei-lin, HU Yun-ying , XUE Shao-bai, . CELL CYCLE PHASE SENSITIVITY OF CHO CELL TO PINGYANGMYCINJ. Acta Pharmaceutica Sinica, 1982, 17(10): 755-760.

CELL CYCLE PHASE SENSITIVITY OF CHO CELL TO PINGYANGMYCIN

  • The effect of Pingyangmycin on relative survival of Chinese hamster ovary cells growing in vitro at various stages in the cell cycle was studied. It was shown that under the dosage used Pingyangmyein is most effective in killing the cells in mitosis and G2 phase. According to their sensitivities to the drug the sensitivity of the cells ranked as follows: M>G2>S>G1.
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