CHEMICAL STUDIES OF SALVIA MILTIORRHIZA F.LBA

Fourteen constituents were isolated from the roots of Salvia miltiorrhiza f. alba. Two of them were new compounds and were named 1, 2, 15, 16-tetrahydrotanshiquinone (Ⅰ) and tanshinaldehyde (Ⅱ). The others were identified as Ro-090680 (Ⅲ), dihydroisotanshone Ⅰ(Ⅳ), danshexinkun B(Ⅴ), miltirone (Ⅵ), nortanshinone (Ⅶ), hydroxytanshinone Ⅱ-A(Ⅷ), tanshinone Ⅰ(Ⅸ), dihydrotanshinone Ⅰ(Ⅹ), tanshinone Ⅱ-A(ⅩⅠ), cryptotanshinone (ⅩⅡ), methylenetanshiquinone (ⅩⅢ), methyltanshinonate (ⅩⅣ), Ⅰ and Ⅲ showed inhibitory activity against P₃₈₈ Leukemia cell in vitro. Ⅲ was reported to be a potent inhibitor of rabbit platelet aggregation induced by collagen.