ZHANG Xiu-ping, YAN Min, SHI Hui-lin , LEI Xing-han, . CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGSJ. Acta Pharmaceutica Sinica, 1984, 19(4): 306-308.
Citation:
ZHANG Xiu-ping, YAN Min, SHI Hui-lin , LEI Xing-han, . CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGSJ. Acta Pharmaceutica Sinica, 1984, 19(4): 306-308.
ZHANG Xiu-ping, YAN Min, SHI Hui-lin , LEI Xing-han, . CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGSJ. Acta Pharmaceutica Sinica, 1984, 19(4): 306-308.
Citation:
ZHANG Xiu-ping, YAN Min, SHI Hui-lin , LEI Xing-han, . CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGSJ. Acta Pharmaceutica Sinica, 1984, 19(4): 306-308.
CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGS
Ten coumaran derivatives were synthesized from the corresponding 2,2'-diphenoI methane or 2,2'-diphenol sulfide derivatives by oxidation. In preliminary screening for prophylactic and curative activities against experimental infection of Schistosomiasis japonica in mice, compound Ⅱ2 was found to be the most active.
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