THE CHEMICAL CONSTITUENTS OF ARISTOLOCILIA MOLLISSlMA HANCE. Ⅳ. DETERMINATION OF CHEMICAL STRUCTURE OF MOLLISLACTONE

Nine chemical constituents (Ⅰ-Ⅸ) were separated from the ethanol extract of the root of Aristolochia mollissima Hance. One of them was found to be a new sesquiterpenoid lactone to which the name mollislactone was suggested. Its formula was identified to be C₁₅H₂₀O₂, mp 134～135℃. The structure of mollislactone was elucidated on the basis of UV, IR, MS, NMR, ¹³C-NMR and ¹³C-PRFT-OFR spectroscopic analyses.The constituents Ⅰ, Ⅱ, Ⅳ and Ⅸ, were identified to be allantoin, aristolactone, β-sitosterol and aristolochic acid respectively. The identification of other constituents is in progress.