IS0LAT10N AND STRUCITURAL ELUCIDATION OF QIANHUCOUMARIN D AND QIANHUCOUMARINE FROM PEUCEDANUM PRAERUPTORUM

Five compounds were isolated from the traditional Chinese medicine Qianhu,rootsof Peucedanum praeruptorum Dunn. Their structures were identified as qianhucoumarin D(I) , PD-Ib(II), qianhucoumarin E(III) ,nodakenetin(IV)and scopoletin(V)by physico-chemical constants andspectral analyses(UV ,IR,lHNMR,¹³CNMR , 2D-NMR,EIMS).I and IIl are new compounds,their structures were elucidated as 3'(S),4'(S)-diacetoxy-3',4'-dihydroseselin(1)and　3'(R)-tigloyloxy-4'-keto-3',4'-dihydroseselin(III)and the absolute configurations were determined bychemical correlations with known compounds.IV and V were first isolated from this plant. The¹HNMR and ¹³CNMR signals of Il were assigned definitely by the experiments of DEPT,¹H-¹HCOSY and 13C-1H COSY.