SHAO Guo-xiao, MO Ruo-ying, ZHU Li-lian , HE Wen-yi, . SYNTHESIS OF LEONURINE AND SYRINGIC ACID AMINOESTERSJ. Acta Pharmaceutica Sinica, 1984, 19(6): 419-424.
Citation: SHAO Guo-xiao, MO Ruo-ying, ZHU Li-lian , HE Wen-yi, . SYNTHESIS OF LEONURINE AND SYRINGIC ACID AMINOESTERSJ. Acta Pharmaceutica Sinica, 1984, 19(6): 419-424.
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SYNTHESIS OF LEONURINE AND SYRINGIC ACID AMINOESTERS

    Abstract
  • In this paper, the synthesis of leonurine (Ⅰ) and a series of syringic acid aminoesters (Ⅲ1～12, Ⅳ1～8) is reported.These compounds showed inhibitory activity against rat platelet aggregation induced by adenosine diphosphate or collagen in vitro. Compounds Ⅲ1, Ⅲ5 and Ⅳ8 were more effective than leonurine. But, δ-guanidino-butanol-1(11) and syringic acid showed little activity.
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