HW Luo, XJ Hu, N Wang , J Ji, . PLATELET AGGREGATION INHIBITORS FROM SALVIA MILTIORRHIZA BUNGEJ. Acta Pharmaceutica Sinica, 1988, 23(11): 830-834.
Citation: HW Luo, XJ Hu, N Wang , J Ji, . PLATELET AGGREGATION INHIBITORS FROM SALVIA MILTIORRHIZA BUNGEJ. Acta Pharmaceutica Sinica, 1988, 23(11): 830-834.
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PLATELET AGGREGATION INHIBITORS FROM SALVIA MILTIORRHIZA BUNGE

    Abstract
  • Five constituents were isolated from Dan-Shen (Salvia miltiorrhiza). Three of them were identified as miltirone (Ⅱ), ferruginol (Ⅰ) and Ro090680 (Ⅲ). The two others were named △1-dehydromiltirone and △1-dehydrotanshinone ⅡA. Ro-090680 has been known as a potent inhibitor of rabbit platelet aggregation in vitro. Related tricyclic diterpenoids such as miltirone and ferruginol were also found to have the same activity.
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