Alkaloids from the root of Lindera angustifolia

AimTo study the alkaloid constituents of the root of Lindera angustifolia Cheng. MethodsThe constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis. ResultsSeven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine (II), boldine (III), isoboldine (IV), norboldine (V), N-ethoxycarbonyllaurotetanine (VII) and a quaternary isoquinoline alkaloid, magnocurarine (VI), were isolated and identified. The structure of VII was further identified by semi-synthesis with I as starting material. ConclusionAll compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time.