CHEMICAL STUDY ON A TRADITIONAL TIBETAN DRUG HYPECOUM LEPTOCARPUM

Four alkaloids were isolated from a traditional Tibetan drug Hypecoum leptocarpum Hook. f. et Thoms. (Fam. Papaveraceae). Three of them were identified as protopine, cryptopine and oxyhydrastinine. The fourth is a new alkaloid, named hypecoumine. On the basis of spectroscopic analysis (UV, IR, MS and IHNMR) its structure was elucidated as (1).