CUI Jin-Yuan, WANG Gui-Zhen. APPLICATION OF ORTHOGONAL FUNCTION SPECTROPHOTOMETRY TO THE DETERMINATION OF COENZYME Q10 CONTENT IN THE INJECTIONJ. Acta Pharmaceutica Sinica, 1985, 20(2): 118-122.
Citation: CUI Jin-Yuan, WANG Gui-Zhen. APPLICATION OF ORTHOGONAL FUNCTION SPECTROPHOTOMETRY TO THE DETERMINATION OF COENZYME Q10 CONTENT IN THE INJECTIONJ. Acta Pharmaceutica Sinica, 1985, 20(2): 118-122.

APPLICATION OF ORTHOGONAL FUNCTION SPECTROPHOTOMETRY TO THE DETERMINATION OF COENZYME Q10 CONTENT IN THE INJECTION

  • This paper reports that the content of coenzyme Q10 injection can be directly determined by orthogonal function spectrophotometry. In alcohol, using the 3-point quadratic polynomial in the wavelength range 286 to 292 nm at 12 nm intervals, the coefficient of the polynomial, P2, provides a precise estimate for coenzyme Q10 and eliminates the interference from TW-80. The mean recovery of coenzyme Q10 is 98.60.66%. This method is simple and the results obtained are satisfactory both in recovery and in precision.
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