AN IMPROVEMENT ON THE WAGNER-NELSON METHOD FOR COMPUTING DRUG ABSORPTION RATE CONSTANT

For one-compartment open model, an equation for computing drug absorption rate constant (k_a) is described equation (9) in the text. The derivation of the equation is independent of the Wagner-Nelson equation. However, the computational procedure of the k_a is similar to the Wagner-Nelson method, the accuracy, is the same, but the computation is simpler.