A new phenolic amide glycoside from Cimicifuga dahurica

A new phenolic amide glycoside, cimicifugamide A (1) along with four known compounds, trans- feruloyl tyramine 4-O-β-D-glucopyranoside (2), (+)-isolariciresinol 3-O-β-D-glucopyranoside (3), cimidahurine (4), and 24-epi-7, 8-didehydrocimigenol-3-O-β-D-xylopyranoside (5) were isolated from the rhizomes of Cimicifuga dahurica.  Compound 3 was identified as a lignan and has been obtained from Cimicifuga genus for the first time.  The structure of compound 1 was elucidated by IR, UV, HR-MS and NMR spectroscopic methods.