ANALEPTICS INTRADITIONAL MEDICINE ANESTHESIA Ⅰ.SYNTHESIS OF m-(ALKYLAMINO) ALKOXYLPHENYL N,N-DIMETHYLCARBAMATES

A series of m-(alkylamino) alkoxylphenyl N,N-dimethyl carbamates were synthesized as potential analeptics in traditional medicine anesthesia. All compounds were tested for toxicity and analeptic activity in experimental animals. The results will be reported elsewhere.Preliminary clinical observations showed that compound Ⅱ₄, introduced under the name of "CUI XING AN", is less toxic and more effective than physostigmine as analeptic in traditional medicine anesthesia.Structure-activity relationships are briefly discussed.