APPLICATION OF MADALINE NEURAL NETWORK IN PHARMACEUTICAL ANALYSIS
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Abstract
AIM To determine the contents of cephalexin (CEX) and trimethoprim (TMP) in compound cephalexin capsules using Madaline neural network. METHODS The overlapping spectra of CEX and TMP were resolved by Madaline neural network into non-overlapping spectra. The maximum absorbance were recorded and used in quantification. RESULTS The average recoveries and RSDs of CEX and TMP were 100.1%, 0.4% and 100.4%, 1.3%, respectively. CONCLUSION Madaline neural network can be used successfully in pharmaceutical analysis.
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