TWO NEW STEROIDAL SAPONINS FROM ALLIUM SATIVUM AND THEIR INHIBITORY EFFECTS ON BLOOD COAGULABILITY

Six compunds were isolated from the fresh bulbs of Allium sativum L(garlic). Their structures were elucidated as proto-iso-eruboside-B (I), eruboside-B (II), iso-eruboside-B (III), sativioside-C (IV), adenosine (V) and tryptophan (VI). I and III are new steroidal saponins. This paper deals with the structural determination of I and III and their effects on platelet aggregation, blood coagulation and fibrinolysis in vitro .