ISOLATION AND IDENTIFICATION OF SESQUITERPENES FROM CREPIS NAPIFERA

AIM　In order to obtain active compounds of the roots of Crepis napifera (Franch) Babc (Compositea), its chemical constituents were studied. METHODS　Solvent partition and gel column chromatography, recrystalization and spectrum were used to extract, isolate and identity the constituents. RESULTS　One sesquiterpene (I) and one triterpene (II) were obtained. (I) and (II) were elucidated as Δ^4,9-dien-eudesmine-13,15-dicarboxylic acid-15-β-D-glucopyranoside (I) and acetate taraxasterol (II) respectively, based on ¹HNMR, ¹³CNMR, ¹H-¹H COSY, HMBC, ROESY, MS and IR spectroscopic data and literature data. CONCLUSION　Compound I is a new eudesmane sesquiterpene glycoside named as napiferosied.