ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZ

Five alkaloids were isolated from the roots of Aconitum finetianum (Hand-Mazz.) by a combination of pH extraction and chromatographic techniques. Chemical and spectral studies suggested that they are a series of the lycoctonine-type alkaloid. Three of them were identified as delsoline, avadharidine and lycoctonine, by comparing their physical properties with known compounds. The formulas of two others alkaloids are designated as C₂₇H₂₁N₃O₅(141～142℃) and C₂₂H₃₁NO₃ (221～226℃). Their structures are under investigation. Delsoline is useful for acute dysentery, acute enteritis and a relaxant of the smooth muscle of intestines.