SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATE

CAI Zu-yun, CHENG Oi-lu, YU Xin-di , NI Yuan, . SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATEJ. Acta Pharmaceutica Sinica, 1982, 17(3): 233-235.

Citation:

CAI Zu-yun, CHENG Oi-lu, YU Xin-di , NI Yuan, . SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATEJ. Acta Pharmaceutica Sinica, 1982, 17(3): 233-235.

Citation:

CAI Zu-yun, CHENG Oi-lu, YU Xin-di , NI Yuan, . SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATEJ. Acta Pharmaceutica Sinica, 1982, 17(3): 233-235.

Abstract

6α-Methyl prednisolone acetate (Ⅸ) was synthesized from 6α-methyl-11β, 17α-dihydroxy progesterone (Ⅶ), which had been obtained through six steps (Ⅰ→Ⅱ→Ⅲ→Ⅳ→Ⅴ→Ⅵ→Ⅶ). The overall yield from Ⅰ to Ⅶ was 17.3%.

FullText(HTML)

Turn off MathJax

Article Contents

Export File