Water-soluble chemical constituents of Swertia davidi Franch.
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Abstract
AimTo study the active constituents of Swertia davidi Franch. MethodsColumn chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR. ResultsThese compounds were elucidated as 8-O-β-D-glucopyranosyl-1,3,5-trihydroxyxanthone (I), 5-O-β-D-glucopyranosyl-1,8-dihydroxy-3-methoxyxanthone (II), 5-O-β-D-glucopyranosyl-1,3,8-trihydroxyxanthone (III) and Swertamarin (IV). ConclusionCompound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time.
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