FH Qiu, L Liu, Y Luo, F Liu, , YQ Lu. SYSTEMATIC ANALYSIS OF BASIC DRUGS IN PLASMA USING X-5 SOLID-PHASE EXTRACTION GC-FID AND GC-MSJ. Acta Pharmaceutica Sinica, 1996, 31(4): 296-299.
Citation:
FH Qiu, L Liu, Y Luo, F Liu, , YQ Lu. SYSTEMATIC ANALYSIS OF BASIC DRUGS IN PLASMA USING X-5 SOLID-PHASE EXTRACTION GC-FID AND GC-MSJ. Acta Pharmaceutica Sinica, 1996, 31(4): 296-299.
FH Qiu, L Liu, Y Luo, F Liu, , YQ Lu. SYSTEMATIC ANALYSIS OF BASIC DRUGS IN PLASMA USING X-5 SOLID-PHASE EXTRACTION GC-FID AND GC-MSJ. Acta Pharmaceutica Sinica, 1996, 31(4): 296-299.
Citation:
FH Qiu, L Liu, Y Luo, F Liu, , YQ Lu. SYSTEMATIC ANALYSIS OF BASIC DRUGS IN PLASMA USING X-5 SOLID-PHASE EXTRACTION GC-FID AND GC-MSJ. Acta Pharmaceutica Sinica, 1996, 31(4): 296-299.
SYSTEMATIC ANALYSIS OF BASIC DRUGS IN PLASMA USING X-5 SOLID-PHASE EXTRACTION GC-FID AND GC-MS
A systematic determination method for 34 hasic drugs in human plasma isdescribed. Drugs were extracted from plasma at pH 10 using X-5 resin as adsorbent,then identifiedand quantitated by capillary GC-FID and GC-MS.The detection limits for most drugs are in the rangeof0.5～2.0μg·ml-1.Precision and linearity of the method are satisfactory for clinical toxicologicalapplications.
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