JS Xia, X Luo , FD Zeng, . EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETSJ. Acta Pharmaceutica Sinica, 1996, 31(11): 872-874.
Citation: JS Xia, X Luo , FD Zeng, . EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETSJ. Acta Pharmaceutica Sinica, 1996, 31(11): 872-874.
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EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS

    Abstract
  • The effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride(DDPH)and verapamil on cytosolic free calcium concentratiOn of rabbitplatelets were investigated.The results showed that the elevation of cytosolic free calciumconcentration(Ca2+i)of rabbit platelets following ionophore A23187 was significantly inhibited byDDPH and verapamil.The rates of inhibition with DDPH and verapamil were 58 % and 78 %,respectively,with no significant difference between the two groups(P>0.05).
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