RT Li, SL Cao, HC Chen, JZ Yang , MS Cai, . SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1,1-DIALKYL-4(3-BKOMOPROPIONYL)PIPERAZINIUM BROMIDESJ. Acta Pharmaceutica Sinica, 1996, 31(10): 757-760.
Citation:
RT Li, SL Cao, HC Chen, JZ Yang , MS Cai, . SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1,1-DIALKYL-4(3-BKOMOPROPIONYL)PIPERAZINIUM BROMIDESJ. Acta Pharmaceutica Sinica, 1996, 31(10): 757-760.
RT Li, SL Cao, HC Chen, JZ Yang , MS Cai, . SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1,1-DIALKYL-4(3-BKOMOPROPIONYL)PIPERAZINIUM BROMIDESJ. Acta Pharmaceutica Sinica, 1996, 31(10): 757-760.
Citation:
RT Li, SL Cao, HC Chen, JZ Yang , MS Cai, . SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1,1-DIALKYL-4(3-BKOMOPROPIONYL)PIPERAZINIUM BROMIDESJ. Acta Pharmaceutica Sinica, 1996, 31(10): 757-760.
SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF 1,1-DIALKYL-4(3-BKOMOPROPIONYL)PIPERAZINIUM BROMIDES
Seven new 1,1-dialkyl-4-(3-bromopropionyl)piperazinium bromides were synthesized.Their structures were elucidated by IR,1H NMR and elemental analysis.The compounds were screened for antitumor,analgesic and antioxide SOD activities。Though none of them showed antitumor activity,most of them shawed distinct analgesic activity and antioxide SOD activity.
DownLoad: