ISOLATION AND IDENTIFICATION OF ALKALOIDS FROM FRITILLARIA ANHUIENSIS S. C. CHEN ET S. F. YIN

Wan Bei Mu, a substitute for the traditional Chinese medicine Bei Mu (Fritillaria verticillata Willd.), has been used for antibechic and expectorant. From Wan Bei Mu (the bulbs of Fritillaria anhuiensis S. C. Chen et S. F. Yin) four alkaloids including a new cevanine alkaloid were isolated. By spectral analysis (IR, MS, ¹HNMR, ¹³CNMR) and preparation of derivative the strucfure of this new alkaloid was elucidated as 5α, 14α, 22β-cevanine-3β,6α,20β-triol, named Wanpeinine A. The known alkaloids were identified as verticinone, peimisine and isoverticine.