THE CORRELATION BETWEEN THE BLOOD Sb LEVEL AND THE THERAPEUTIC EFFECT OF TARTAR EMETIC IN SCHISTOSOMIASIS OF RABBITS

The oral administration of tartar emetic to rabbits infected schistosomiasis can produces a certain degree of effectiveness, but the Sb content is not parallel with the oral dosage used. No correlation between the blood Sb content and the therapeutic effect was observed. The blood Sb content in the group of animals treated by intravenous dripping of tartars emetic is markedly lower than that in rabbits receiving the same dosage in 6 i.v. injections, but the therapeutic effects are just the same in both groups. The assumption that higher level of blood Sb will bring about better therapeutic effect is not confirmed. The urinary Sb content runs parallel with the dosage used. This therefore, suggests that in order to know the absorption of Sb after its oral administration, urinary Sb may be determined instead of blood Sb content.