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New opportunities and challenges of natural products research: When target identification meets single-cell multiomics
Yuyu Zhu, Zijun Ouyang, Haojie Du, Meijing Wang, Jiaojiao Wang, Haiyan Sun, Lingdong Kong, Qiang Xu, Hongyue Ma, Yang Sun,
2022, 12(11):4011-4039. DOI:10.1016/j.apsb.2022.08.022
Abstract
The anti-inflammatory feature of glucagon-like peptide-1 and its based diabetes drugs—Therapeutic potential exploration in lung injury
Juan Pang, Jia Nuo Feng, Wenhua Ling, Tianru Jin,
2022, 12(11):4040-4055. DOI:10.1016/j.apsb.2022.06.003
Abstract
Small molecules for combating multidrug-resistant superbug Candida auris infections
Jie Tu, Na Liu, Yahui Huang, Wanzhen Yang, Chunquan Sheng,
2022, 12(11):4056-4074. DOI:10.1016/j.apsb.2022.08.001
Abstract
Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses
Shilin Chen, Zheng Li, Sanyin Zhang, Yuxin Zhou, Xiaohe Xiao, Pengdi Cui, Binjie Xu, Qinghe Zhao, Shasha Kong, Yuntao Dai,
2022, 12(11):4075-4097. DOI:10.1016/j.apsb.2022.08.025
Abstract
Smart drug delivery systems for precise cancer therapy
Xiaoyou Wang, Chong Li, Yiguang Wang, Huabing Chen, Xinxin Zhang, Cong Luo, Wenhu Zhou, Lili Li, Lesheng Teng, Haijun Yu, Jiancheng Wang,
2022, 12(11):4098-4121. DOI:10.1016/j.apsb.2022.08.013
Abstract
Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo
Fanxiang Yin, Ran Zhao, Dhilli Rao Gorja, Xiaorong Fu, Ning Lu, Hai Huang, Beibei Xu, Hanyong Chen, Jung-Hyun Shim, Kangdong Liu, Zhi Li, Kyle Vaughn Laster, Zigang Dong, Mee-Hyun Lee,
2022, 12(11):4122-4137. DOI:10.1016/j.apsb.2022.07.005
Abstract
Cardiac fibroblast heat shock protein 47 aggravates cardiac fibrosis post myocardial ischemia-reperfusion injury by encouraging ubiquitin specific peptidase 10 dependent Smad4 deubiquitination
Saiyang Xie, Yun Xing, Wenke Shi, Min Zhang, Mengya Chen, Wenxi Fang, Shiqiang Liu, Tong Zhang, Xiaofeng Zeng, Si Chen, Shasha Wang, Wei Deng, Qizhu Tang,
2022, 12(11):4138-4153. DOI:10.1016/j.apsb.2022.07.022
Abstract
Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19
Yang Yi, Meng Zhang, Heng Xue, Rong Yu, Yang-Oujie Bao, Yi Kuang, Yue Chai, Wen Ma, Jing Wang, Xiaomeng Shi, Wenzhe Li, Wei Hong, Junhua Li, Elishiba Muturi, Hongping Wei, Joachim Wlodarz, Szczepan Roszak, Xue Qiao, Hang Yang, Min Ye,
2022, 12(11):4154-4164. DOI:10.1016/j.apsb.2022.07.017
Abstract
A novel inhibitor of ARfl and ARv7 induces protein degradation to overcome enzalutamide resistance in advanced prostate cancer
Yan Li, Ya Chu, Guangjiang Shi, Xiaobin Wang, Wanli Ye, Chun Shan, Dajia Wang, Di Zhang, Wei He, Jingwei Jiang, Shuqian Ma, Yuhong Han, Zhili Zhao, Shijia Du, Zhen Chen, Zhiyu Li, Yong Yang, Chen Wang, Xi Xu, Hongxi Wu,
2022, 12(11):4165-4179. DOI:10.1016/j.apsb.2022.05.003
Abstract
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6
Liping Liao, Wenzhen Dang, Tingting Lin, Jinghua Yu, Tonghai Liu, Wen Li, Senhao Xiao, Lei Feng, Jing Huang, Rong Fu, Jiacheng Li, Liping Liu, Mingchen Wang, Hongru Tao, Hualiang Jiang, Kaixian Chen, Xingxing Diao, Bing Zhou, Xiaoyan Shen, Cheng Luo,
2022, 12(11):4180-4192. DOI:10.1016/j.apsb.2022.05.012
Abstract
Biosynthesis of rumbrins and inspiration for discovery of HIV inhibitors
Beifen Zhong, Jun Wan, Changhui Shang, Jiajia Wen, Yujia Wang, Jian Bai, Shan Cen, Youcai Hu,
2022, 12(11):4193-4203. DOI:10.1016/j.apsb.2022.02.005
Abstract
Cascade two-stage tumor re-oxygenation and immune re-sensitization mediated by self-assembled albumin-sorafenib nanoparticles for enhanced photodynamic immunotherapy
Zaigang Zhou, Jiashe Chen, Yu Liu, Chunjuan Zheng, Wenjuan Luo, Lele Chen, Shen Zhou, Zhiming Li, Jianliang Shen,
2022, 12(11):4204-4223. DOI:10.1016/j.apsb.2022.07.023
Abstract
Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy
Zekun Li, Yongchun Pan, Shiyu Du, Yayao Li, Chao Chen, Hongxiu Song, Yueyao Wu, Xiaowei Luan, Qin Xu, Xiaoxiang Guan, Yujun Song, Xin Han,
2022, 12(11):4224-4234. DOI:10.1016/j.apsb.2022.06.016
Abstract
Broad-spectrum and powerful neutralization of bacterial toxins by erythroliposomes with the help of macrophage uptake and degradation
Chunying Liu, Shuangrong Ruan, Ying He, Xuejing Li, Yuefei Zhu, Honglan Wang, Hanwei Huang, Zhiqing Pang,
2022, 12(11):4235-4248. DOI:10.1016/j.apsb.2022.03.015
Abstract
Site-selective oral delivery of therapeutic antibodies to the inflamed colon via a folic acid-grafted organic/inorganic hybrid nanocomposite system
Sang Hoon Lee, Jae Geun Song, Hyo-Kyung Han,
2022, 12(11):4249-4261. DOI:10.1016/j.apsb.2022.06.006
Abstract
PROTAC technology as a novel tool to identify the target of lathyrane diterpenoids
Yanli Wu, Yueying Yang, Wang Wang, Dejuan Sun, Jing Liang, Man Zhu, Hua Li, Lixia Chen,
2022, 12(11):4262-4265. DOI:10.1016/j.apsb.2022.07.007
Abstract
Drug discovery in China: A snapshot of recent progress
Hongxi Hu, Cuicui Xie, Huiyan Xu, Liyun Zhou,
2022, 12(11):4266-4269. DOI:10.1016/j.apsb.2022.08.021
Abstract

Copyright © 2014 Editorial Office of Acta Pharmaceutica Sinica