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mRNA cancer vaccines: Advances, trends and challenges
Qing He, Hua Gao, Dejiang Tan, Heng Zhang, Jun-zhi Wang,
2022, 12(7):2969-2989. DOI:10.1016/j.apsb.2022.03.011
Abstract
Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope
Sinan Ma, Jianai Ji, Yuanyuan Tong, Yuxuan Zhu, Junwei Dou, Xian Zhang, Shicheng Xu, Tianbao Zhu, Xiaoli Xu, Qidong You, Zhengyu Jiang,
2022, 12(7):2990-3005. DOI:10.1016/j.apsb.2022.02.022
Abstract
Target-based anticancer indole derivatives and insight into structure-activity relationship: A mechanistic review update (2018–2021)
Ashima Dhiman, Rupam Sharma, Rajesh K. Singh,
2022, 12(7):3006-3027. DOI:10.1016/j.apsb.2022.03.021
Abstract
Current approaches of nanomedicines in the market and various stage of clinical translation
Xiaoting Shan, Xiang Gong, Jie Li, Jingyuan Wen, Yaping Li, Zhiwen Zhang,
2022, 12(7):3028-3048. DOI:10.1016/j.apsb.2022.02.025
Abstract
Why 90% of clinical drug development fails and how to improve it?
Duxin Sun, Wei Gao, Hongxiang Hu, Simon Zhou,
2022, 12(7):3049-3062. DOI:10.1016/j.apsb.2022.02.002
Abstract
Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
Yi Zhu, Na Li, Mingyang Huang, Xi Chen, Yu A. An, Jianping Li, Shangang Zhao, Jan-Bernd Funcke, Jianhong Cao, Zhenyan He, Qingzhang Zhu, Zhuzhen Zhang, Zhao V. Wang, Lin Xu, Kevin W. Williams, Chien Li, Kevin Grove, Philipp E. Scherer,
2022, 12(7):3063-3072. DOI:10.1016/j.apsb.2022.02.020
Abstract
Targeting macrophagic SHP2 for ameliorating osteoarthritis via TLR signaling
Ziying Sun, Qianqian Liu, Zhongyang Lv, Jiawei Li, Xingquan Xu, Heng Sun, Maochun Wang, Kuoyang Sun, Tianshu Shi, Zizheng Liu, Guihua Tan, Wenqiang Yan, Rui Wu, Yannick Xiaofan Yang, Shiro Ikegawa, Qing Jiang, Yang Sun, Dongquan Shi,
2022, 12(7):3073-3084. DOI:10.1016/j.apsb.2022.02.010
Abstract
Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma
Ningna Weng, Siyuan Qin, Jiayang Liu, Xing Huang, Jingwen Jiang, Li Zhou, Zhe Zhang, Na Xie, Kui Wang, Ping Jin, Maochao Luo, Liyuan Peng, Edouard C. Nice, Ajay Goel, Suxia Han, Canhua Huang, Qing Zhu,
2022, 12(7):3085-3102. DOI:10.1016/j.apsb.2022.01.018
Abstract
Structure-based discovery of orally efficient inhibitors via unique interactions with H-pocket of PDE8 for the treatment of vascular dementia
Xu-Nian Wu, Qian Zhou, Ya-Dan Huang, Xi Xie, Zhe Li, Yinuo Wu, Hai-Bin Luo,
2022, 12(7):3103-3112. DOI:10.1016/j.apsb.2022.02.012
Abstract
Screening potential P-glycoprotein inhibitors by combination of a detergent-free membrane protein extraction with surface plasmon resonance biosensor
Yuhong Cao, Jiahao Fang, Yiwei Shi, Hui Wang, Xiaofei Chen, Yue Liu, Zhenyu Zhu, Yan Cao, Zhanying Hong, Yifeng Chai,
2022, 12(7):3113-3123. DOI:10.1016/j.apsb.2022.03.016
Abstract
Gold nanoparticle-directed autophagy intervention for antitumor immunotherapy via inhibiting tumor-associated macrophage M2 polarization
Siyue Zhang, Fangyuan Xie, Kaichun Li, He Zhang, You Yin, Yuan Yu, Guangzhao Lu, Shihao Zhang, Yan Wei, Ke Xu, Yan Wu, Hong Jin, Lan Xiao, Leilei Bao, Can Xu, Yulin Li, Ying Lu, Jie Gao,
2022, 12(7):3124-3138. DOI:10.1016/j.apsb.2022.02.008
Abstract
Engineering prodrug nanomicelles as pyroptosis inducer for codelivery of PI3K/mTOR and CDK inhibitors to enhance antitumor immunity
Qichao Yang, Xianbin Ma, Yao Xiao, Tian Zhang, Leilei Yang, Shaochen Yang, Mengyun Liang, Shuo Wang, Zhizhong Wu, Zhigang Xu, Zhijun Sun,
2022, 12(7):3139-3155. DOI:10.1016/j.apsb.2022.02.024
Abstract
Biological fate and interaction with cytochromes P450 of the nanocarrier material, d-α-tocopheryl polyethylene glycol 1000 succinate
Tianming Ren, Runzhi Li, Liqiang Zhao, J. Paul Fawcett, Dong Sun, Jingkai Gu,
2022, 12(7):3156-3166. DOI:10.1016/j.apsb.2022.01.014
Abstract
Metabolic engineering of yeasts for green and sustainable production of bioactive ginsenosides F2 and 3β,20S-Di-O-Glc-DM
Fenglin Jiang, Chen Zhou, Yan Li, Haidong Deng, Ting Gong, Jingjing Chen, Tianjiao Chen, Jinling Yang, Ping Zhu,
2022, 12(7):3167-3176. DOI:10.1016/j.apsb.2022.04.012
Abstract
Generation of αGal-enhanced bifunctional tumor vaccine
Jian He, Yu Huo, Zhikun Zhang, Yiqun Luo, Xiuli Liu, Qiaoying Chen, Pan Wu, Wei Shi, Tao Wu, Chao Tang, Huixue Wang, Lan Li, Xiyu Liu, Yong Huang, Yongxiang Zhao, Lu Gan, Bing Wang, Liping Zhong,
2022, 12(7):3177-3186. DOI:10.1016/j.apsb.2022.03.002
Abstract
Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants
Bin Tu, Huiyuan Wang, Xinran An, Jingkun Qu, Qianqian Li, Yanrong Gao, Mingjie Shi, Hong Qiu, Yongzhuo Huang,
2022, 12(7):3187-3194. DOI:10.1016/j.apsb.2022.01.019
Abstract
Viral miRNA-mediated activation of hyaluronan production as a drug target against COVID-19
Shuai Yang, Lu Chen, Ying Tong, Wenqiang Yu,
2022, 12(7):3195-3197. DOI:10.1016/j.apsb.2022.03.022
Abstract
Author correction to ‘Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4 signaling’ [Acta Pharmaceutica Sinica B 12 (2022) 1198–1212]
Yunhao Wu, Xiu Yu, Yuwei Wang, Yalin Huang, Jiahui Tang, Shuaishuai Gong, Siyu Jiang, Yuanli Xia, Fang Li, Boyang Yu, Yuanyuan Zhang, Junping Kou,
2022, 12(7):3198-3199. DOI:10.1016/j.apsb.2022.04.004
Abstract

Copyright © 2014 Editorial Office of Acta Pharmaceutica Sinica