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Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients
Solène Marie, Kayla L. Frost, Raymond K. Hau, Lucy Martinez-Guerrero, Jailyn M. Izu, Cassandra M. Myers, Stephen H. Wright, Nathan J. Cherrington,
2023, 13(1):1-28. DOI:10.1016/j.apsb.2022.08.018
Abstract
Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies
Panat Yanpiset, Chayodom Maneechote, Sirawit Sriwichaiin, Natthaphat Siri-Angkul, Siriporn C. Chattipakorn, Nipon Chattipakorn,
2023, 13(1):29-53. DOI:10.1016/j.apsb.2022.08.007
Abstract
Kinome-wide polypharmacology profiling of small molecules by multi-task graph isomorphism network approach
Lingjie Bao, Zhe Wang, Zhenxing Wu, Hao Luo, Jiahui Yu, Yu Kang, Dongsheng Cao, Tingjun Hou,
2023, 13(1):54-67. DOI:10.1016/j.apsb.2022.05.004
Abstract
CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain
Lili Sun, Jie Zhang, Changshan Niu, Cassandra E. Deering-Rice, Ronald W. Hughen, John G. Lamb, Katherine Rose, Kevin M. Chase, Marysol Almestica-Roberts, Markel Walter, Eric W. Schmidt, Alan R. Light, Baldomero M. Olivera, Christopher A. Reilly,
2023, 13(1):68-81. DOI:10.1016/j.apsb.2022.09.007
Abstract
Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids
Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Javier Burgueño, Xavier Monroy, Bertrand Aubel, Xavier Codony, Luz Romero, Rosalía Pascual, Maria Teresa Serafini, Gregorio Encina, Carmen Almansa, Daniel Zamanillo, Manuel Merlos, José Miguel Vela,
2023, 13(1):82-99. DOI:10.1016/j.apsb.2022.09.018
Abstract
Melatonin alleviates alcoholic liver disease via EGFR-BRG1-TERT axis regulation
Zhaodi Che, Yali Song, Chengfang Xu, Wei Li, Zhiyong Dong, Cunchuan Wang, Yixing Ren, Kwok-Fai So, George L. Tipoe, Fei Wang, Jia Xiao,
2023, 13(1):100-112. DOI:10.1016/j.apsb.2022.06.015
Abstract
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS
Xunxun Wu, Lian Liu, Qiuling Zheng, Hui Ye, Hua Yang, Haiping Hao, Ping Li,
2023, 13(1):113-127. DOI:10.1016/j.apsb.2022.07.006
Abstract
Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged-1-Notch1
Rong Chen, Shiqing Zhang, Fang Liu, Lin Xia, Chong Wang, Siamak Sandoghchian Shotorbani, Huaxi Xu, Subrata Chakrabarti, Tianqing Peng, Zhaoliang Su,
2023, 13(1):128-141. DOI:10.1016/j.apsb.2022.08.016
Abstract
Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease
Xiaoyu Dong, Yiting Feng, Dongqin Xu, Mengya Zhang, Xiao Wen, Wenhao Zhao, Qintong Hu, Qinyong Zhang, Hui Fu, Jie Ping,
2023, 13(1):142-156. DOI:10.1016/j.apsb.2022.04.003
Abstract
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
Mingming Sun, Leilei Li, Yujia Niu, Yingzhi Wang, Qi Yan, Fei Xie, Yaya Qiao, Jiaqi Song, Huanran Sun, Zhen Li, Sizhen Lai, Hongkai Chang, Han Zhang, Jiyan Wang, Chenxin Yang, Huifang Zhao, Junzhen Tan, Yanping Li, Shuangping Liu, Bin Lu, Min Liu, Guangyao Kong, Yujun Zhao, Chunze Zhang, Shu-Hai Lin, Cheng Luo, Shuai Zhang, Changliang Shan,
2023, 13(1):157-173. DOI:10.1016/j.apsb.2022.05.019
Abstract
Vitisin B inhibits influenza A virus replication by multi-targeting neuraminidase and virus-induced oxidative stress
Eun-Bin Kwon, Wei Li, Young Soo Kim, Buyun Kim, Hwan-Suck Chung, Younghoon Go, Hyun-Jeong Ko, Jae-Hyoung Song, Young Ho Kim, Chun Whan Choi, Jang-Gi Choi,
2023, 13(1):174-191. DOI:10.1016/j.apsb.2022.07.001
Abstract
Reactivation of PPARα alleviates myocardial lipid accumulation and cardiac dysfunction by improving fatty acid β-oxidation in Dsg2-deficient arrhythmogenic cardiomyopathy
Yubi Lin, Ruonan Liu, Yanling Huang, Zhe Yang, Jianzhong Xian, Jingmin Huang, Zirui Qiu, Xiufang Lin, Mengzhen Zhang, Hui Chen, Huadong Wang, Jiana Huang, Geyang Xu,
2023, 13(1):192-203. DOI:10.1016/j.apsb.2022.05.018
Abstract
Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
Benjamin L. Prather, Shuyue Ji, Yue Zhao, Femil Joseph Shajan, Mi Zhao, Zakey Yusuf Buuh, Robert Maloney, Rui Zhang, Carson Cohen, Rongsheng E. Wang,
2023, 13(1):204-212. DOI:10.1016/j.apsb.2022.08.003
Abstract
Structure-activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4
Ahmed Haider, Xiaoyun Deng, Olivia Mastromihalis, Stefanie K. Pfister, Troels E. Jeppesen, Zhiwei Xiao, Vi Pham, Shaofa Sun, Jian Rong, Chunyu Zhao, Jiahui Chen, Yinlong Li, Theresa R. Connors, April T. Davenport, James B. Daunais, Vahid Hosseini, Wenqing Ran, Arthur Christopoulos, Lu Wang, Celine Valant, Steven H. Liang,
2023, 13(1):213-226. DOI:10.1016/j.apsb.2022.07.008
Abstract
Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin
Shijin Hong, Shuai Li, Xiaoyan Meng, Ping Li, Xun Wang, Mengxiang Su, Xiaodong Liu, Li Liu,
2023, 13(1):227-245. DOI:10.1016/j.apsb.2022.06.010
Abstract
Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C-glycoside cleaving enzyme and an O- to C-glycoside isomerase
Pengfei He, Sha Wang, Sen Li, Siqi Liu, Shuqi Zhou, Jing Wang, Jiayue Tao, Dongdong Wang, Rufeng Wang, Wenfu Ma,
2023, 13(1):246-255. DOI:10.1016/j.apsb.2022.05.022
Abstract
Late-stage cascade of oxidation reactions during the biosynthesis of oxalicine B in Penicillium oxalicum
Tao Zhang, Guowei Gu, Guodong Liu, Jinhua Su, Zhilai Zhan, Jianyuan Zhao, Jinxiu Qian, Guowei Cai, Shan Cen, Dewu Zhang, Liyan Yu,
2023, 13(1):256-270. DOI:10.1016/j.apsb.2022.09.008
Abstract
Functional characterization of a cycloartenol synthase and four glycosyltransferases in the biosynthesis of cycloastragenol-type astragalosides from Astragalus membranaceus
Yangyang Duan, Wenyu Du, Zhijun Song, Ridao Chen, Kebo Xie, Jimei Liu, Dawei Chen, Jungui Dai,
2023, 13(1):271-283. DOI:10.1016/j.apsb.2022.05.015
Abstract
Bilayer hydrogel dressing with lysozyme-enhanced photothermal therapy for biofilm eradication and accelerated chronic wound repair
Yizhen Wang, Qijun Lv, You Chen, Langtao Xu, Miao Feng, Zhiyong Xiong, Jiajun Li, Jie Ren, Jie Liu, Bo Liu,
2023, 13(1):284-297. DOI:10.1016/j.apsb.2022.03.024
Abstract
A neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like cells by redox microenvironment modulation and hypoxia-triggered differentiation therapy
Yongchao Chu, Yifan Luo, Boyu Su, Chao Li, Qin Guo, Yiwen Zhang, Peixin Liu, Hongyi Chen, Zhenhao Zhao, Zheng Zhou, Yu Wang, Chen Jiang, Tao Sun,
2023, 13(1):298-314. DOI:10.1016/j.apsb.2022.05.027
Abstract
Predatory bacterial hydrogels for topical treatment of infected wounds
Yan Liu, Bo Zhuang, Bochuan Yuan, Hui Zhang, Jingfei Li, Wanmei Wang, Ruiteng Li, Lina Du, Pingtian Ding, Yiguang Jin,
2023, 13(1):315-326. DOI:10.1016/j.apsb.2022.05.005
Abstract
Macrophage-evading and tumor-specific apoptosis inducing nanoparticles for targeted cancer therapy
Zimo Liu, Xuefei Zhou, Qi Li, Youqing Shen, Tianhua Zhou, Xiangrui Liu,
2023, 13(1):327-343. DOI:10.1016/j.apsb.2022.05.010
Abstract
Actively separated microneedle patch for sustained-release of growth hormone to treat growth hormone deficiency
Li Yang, Qingyun Liu, Xinhui Wang, Nansha Gao, Xiuzhen Li, Hongzhong Chen, Lin Mei, Xiaowei Zeng,
2023, 13(1):344-358. DOI:10.1016/j.apsb.2022.04.015
Abstract
All-stage targeted therapy for the brain metastasis from triple-negative breast cancer
Zimiao Luo, Sunyi Wu, Jianfen Zhou, Weixia Xu, Qianzhu Xu, Linwei Lu, Cao Xie, Yu Liu, Weiyue Lu,
2023, 13(1):359-371. DOI:10.1016/j.apsb.2022.03.026
Abstract
Highly sensitive H2O2-scavenging nano-bionic system for precise treatment of atherosclerosis
Xiaoyu Liang, Huiyang Li, Xuanling Li, Xinxin Tian, Aiai Zhang, Qingzhi Luo, Jianwei Duan, Youlu Chen, Liyun Pang, Chen Li, Xing-Jie Liang, Yong Zeng, Jing Yang,
2023, 13(1):372-389. DOI:10.1016/j.apsb.2022.04.002
Abstract
Pathologically triggered in situ aggregation of nanoparticles for inflammation-targeting amplification and therapeutic potentiation
Qiang Nie, Chenwen Li, Yu Wang, Yi Hu, Wendan Pu, Qixiong Zhang, Jiajun Cai, Yongyao Lin, Gang Li, Chenping Wang, Lanlan Li, Yin Dou, Jianxiang Zhang,
2023, 13(1):390-409. DOI:10.1016/j.apsb.2022.07.013
Abstract
Chlorella sp.-ameliorated undesirable microenvironment promotes diabetic wound healing
Hangyi Wu, Pei Yang, Aiqin Li, Xin Jin, Zhenhai Zhang, HuiXia Lv,
2023, 13(1):410-424. DOI:10.1016/j.apsb.2022.06.012
Abstract
Sialic acid-mediated photochemotherapy enhances infiltration of CD8+ T cells from tumor-draining lymph nodes into tumors of immunosenescent mice
Dezhi Sui, Changzhi Li, Xueying Tang, Xianmin Meng, Junqiang Ding, Qiongfen Yang, Zhaowei Qi, Xinrong Liu, Yihui Deng, Yanzhi Song,
2023, 13(1):425-439. DOI:10.1016/j.apsb.2022.06.005
Abstract
Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
Guan Wang, Yongya Wu, Chengyong Wu, Wen Shuai, Tingting Jiang, Aoxue Wang, Faqian Bu, Qiu Sun, Liang Ouyang,
2023, 13(1):440-443. DOI:10.1016/j.apsb.2022.10.012
Abstract

Copyright © 2014 Editorial Office of Acta Pharmaceutica Sinica