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Expression and functions of transient receptor potential channels in liver diseases
Wenhui Wang, Pengyu Liu, Yalin Zhang, Li Yan, Michael X. Zhu, Jin Wang, Ye Yu,
2023, 13(2):445-459. DOI:10.1016/j.apsb.2022.09.005
Abstract
Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy
Zhengjie Lu, Yu Guo, Dan Xu, Hao Xiao, Yongguo Dai, Kexin Liu, Liaobin Chen, Hui Wang,
2023, 13(2):460-477. DOI:10.1016/j.apsb.2022.05.029
Abstract
Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
Yeuan Ting Lee, Yi Jer Tan, Chern Ein Oon,
2023, 13(2):478-497. DOI:10.1016/j.apsb.2022.09.010
Abstract
Peptide–drug conjugates (PDCs): a novel trend of research and development on targeted therapy, hype or hope?
Chen Fu, Lifeng Yu, Yuxi Miao, Xinli Liu, Zhaojin Yu, Minjie Wei,
2023, 13(2):498-516. DOI:10.1016/j.apsb.2022.07.020
Abstract
Medical micro- and nanomotors in the body
Huaan Li, Fei Peng, Xiaohui Yan, Chun Mao, Xing Ma, Daniela A. Wilson, Qiang He, Yingfeng Tu,
2023, 13(2):517-541. DOI:10.1016/j.apsb.2022.10.010
Abstract
Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs–EBP interaction recover NAFLD through enhancing mitochondrial function in mice
Nazi Song, Hongjiao Xu, Shuohan Wu, Suijia Luo, Jingyao Xu, Qian Zhao, Rui Wang, Xianxing Jiang,
2023, 13(2):542-558. DOI:10.1016/j.apsb.2022.10.003
Abstract
SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR
Shuang Cui, Huijian Hu, An Chen, Ming Cui, Xiaojie Pan, Pengfei Zhang, Guangji Wang, Hong Wang, Haiping Hao,
2023, 13(2):559-576. DOI:10.1016/j.apsb.2022.08.019
Abstract
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis
Yujun Zhou, Jingshu Tang, Jiaqi Lan, Yong Zhang, Hongyue Wang, Qiuyu Chen, Yuying Kang, Yang Sun, Xinhong Feng, Lei Wu, Hongtao Jin, Shizhong Chen, Ying Peng,
2023, 13(2):577-597. DOI:10.1016/j.apsb.2022.07.019
Abstract
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia
Yin Feng, Yefan Han, Anni Hu, Yi Qu, Yili Hu, Hao Wu, Xinzhi Wang, Li He,
2023, 13(2):598-617. DOI:10.1016/j.apsb.2022.10.018
Abstract
Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism
Changpei Gan, Jing Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Els Wagenaar, Yaogeng Wang, Maria C. Lebre, Hilde Rosing, Sjoerd Klarenbeek, Rahmen Bin Ali, Colin Pritchard, Ivo Huijbers, Jos H. Beijnen, Alfred H. Schinkel,
2023, 13(2):618-631. DOI:10.1016/j.apsb.2022.10.017
Abstract
Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma
Jizhou Tan, Ting Liu, Wenzhe Fan, Jialiang Wei, Bowen Zhu, Yafang Liu, Lingwei Liu, Xiaokai Zhang, Songling Chen, Haibiao Lin, Yuanqing Zhang, Jiaping Li,
2023, 13(2):632-647. DOI:10.1016/j.apsb.2022.08.006
Abstract
The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia
Jian Lu, Xuyang Shang, Bingyi Yao, Dongyi Sun, Jie Liu, Yuanjin Zhang, He Wang, Jingru Shi, Huaqing Chen, Tieliu Shi, Mingyao Liu, Xin Wang,
2023, 13(2):648-661. DOI:10.1016/j.apsb.2022.08.005
Abstract
Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson's disease
Yang Liu, Ting Liu, Yuanzhang Zhou, Wenjie Li, Min Wang, Nanshan Song, Wenbin Zhang, Jingwei Jiang, Shengtao Yuan, Jianhua Ding, Gang Hu, Ming Lu,
2023, 13(2):662-677. DOI:10.1016/j.apsb.2022.07.021
Abstract
Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases
Haowen Xu, Jiahao Chen, Pan Chen, Weifeng Li, Jingjing Shao, Shanshan Hong, Yi Wang, Lingfeng Chen, Wu Luo, Guang Liang,
2023, 13(2):678-693. DOI:10.1016/j.apsb.2022.09.014
Abstract
PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy
Di Zhao, Jing Zhang, Lingyuan Zhang, Qingnan Wu, Yan Wang, Weimin Zhang, Yuanfan Xiao, Jie Chen, Qimin Zhan,
2023, 13(2):694-708. DOI:10.1016/j.apsb.2022.08.014
Abstract
Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators
Siyuan Tang, Miguel Garzon Sanz, Oliver Smith, Andreas Krämer, Daniel Egbase, Paul W. Caton, Stefan Knapp, Sam Butterworth,
2023, 13(2):709-721. DOI:10.1016/j.apsb.2022.07.016
Abstract
A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis
Dan Wang, Bochuan Deng, Lu Cheng, Jieru Li, Jiao Zhang, Xiang Zhang, Xiaomin Guo, Tiantian Yan, Xin Yue, Yingying An, Bangzhi Zhang, Wenle Yang, Junqiu Xie, Rui Wang,
2023, 13(2):722-738. DOI:10.1016/j.apsb.2022.09.001
Abstract
Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia
Zhifu Xie, Mei Zhang, Qian Song, Long Cheng, Xinwen Zhang, Gaolei Song, Xinyu Sun, Min Gu, Chendong Zhou, Yangming Zhang, Kexin Zhu, Jianpeng Yin, Xiaoyan Chen, Jingya Li, Fajun Nan,
2023, 13(2):739-753. DOI:10.1016/j.apsb.2022.06.011
Abstract
(+)/(−)-Yanhusamides A−C, three pairs of unprecedented benzylisoquinoline-pyrrole hetero-dimeric alkaloid enantiomers from Corydalis yanhusuo
Lingyan Wang, Guiyang Xia, Huan Xia, Xiaohong Wei, Yanan Wang, Sheng Lin,
2023, 13(2):754-764. DOI:10.1016/j.apsb.2022.10.025
Abstract
Insights into the biosynthesis of septacidin l-heptosamine moiety unveils a VOC family sugar epimerase
Meng Chen, Zhengyan Guo, Jinyuan Sun, Wei Tang, Min Wang, Yue Tang, Pengwei Li, Bian Wu, Yihua Chen,
2023, 13(2):765-774. DOI:10.1016/j.apsb.2022.05.031
Abstract
A metabolic intervention strategy to break evolutionary adaptability of tumor for reinforced immunotherapy
Qianhua Feng, Yutong Hao, Shuaiqi Yang, Xiaomin Yuan, Jing Chen, Yuying Mei, Lanlan Liu, Junbiao Chang, Zhenzhong Zhang, Lei Wang,
2023, 13(2):775-786. DOI:10.1016/j.apsb.2022.10.021
Abstract
Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy
Yijun Chen, Kaiming Li, Mengying Jiao, Yingshuang Huang, Zihao Zhang, Lingjing Xue, Caoyun Ju, Can Zhang,
2023, 13(2):787-803. DOI:10.1016/j.apsb.2022.08.012
Abstract
A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence
Tao He, Mingxing Hu, Shunyao Zhu, Meiling Shen, Xiaorong Kou, Xiuqi Liang, Lu Li, Xinchao Li, Miaomiao Zhang, Qinjie Wu, Changyang Gong,
2023, 13(2):804-818. DOI:10.1016/j.apsb.2022.09.017
Abstract
Salmonella-mediated blood‒brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy
Ze Mi, Qing Yao, Yan Qi, Jinhai Zheng, Jiahao Liu, Zhenguo Liu, Hongpei Tan, Xiaoqian Ma, Wenhu Zhou, Pengfei Rong,
2023, 13(2):819-833. DOI:10.1016/j.apsb.2022.09.016
Abstract
Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming
Dayuan Wang, Xiao Gu, Xinyi Ma, Jun Chen, Qizhi Zhang, Zhihua Yu, Juan Li, Meng Hu, Xiaofang Tan, Yuyun Tang, Jianrong Xu, Minjun Xu, Qingxiang Song, Huahua Song, Gan Jiang, Zaiming Tang, Xiaoling Gao, Hongzhuan Chen,
2023, 13(2):834-851. DOI:10.1016/j.apsb.2022.07.014
Abstract
Precise assembly of inside-out cell membrane camouflaged nanoparticles via bioorthogonal reactions for improving drug leads capturing
Xiaolin Zhang, Xueyan Zhen, Yixuan Yang, Quan Feng, Wanqing Yuan, Xiaoyu Xie,
2023, 13(2):852-862. DOI:10.1016/j.apsb.2022.05.034
Abstract
Iron-based and BRD4-downregulated strategy for amplified ferroptosis based on pH-sensitive/NIR-II-boosted nano-matchbox
Lujing Geng, Tong Lu, Huaqing Jing, Yue Zhou, Xiaoyang Liang, Jiao Li, Nan Li,
2023, 13(2):863-878. DOI:10.1016/j.apsb.2022.05.011
Abstract
Photosensitive pro-drug nanoassemblies harboring a chemotherapeutic dormancy function potentiates cancer immunotherapy
Jianjun Cheng, Haitian Zhao, Bin Li, Hua Zhang, Qianyu Zhao, Shiyao Fu, Ying Han, Weihong Lu, Jiahua Shi, Xin Yang,
2023, 13(2):879-896. DOI:10.1016/j.apsb.2022.06.008
Abstract
Author correction to ‘Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy’ [Acta Pharmaceutica Sinica B 11 (2021) 3508–3526]
Shuyi Wang, Jun Tao, Huaguo Chen, Machender R. Kandadi, Mingming Sun, Haixia Xu, Gary D. Lopaschuk, Yan Lu, Junmeng Zheng, Hu Peng, Jun Ren,
2023, 13(2):897-898. DOI:10.1016/j.apsb.2022.12.015
Abstract
Author correction to ‘Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models’ [Acta Pharmaceutica Sinica B 11(2021) 1903–1913]
Ziru Yu, Dewen Kong, Yu Liang, Xiaoyue Zhao, Guanhua Du,
2023, 13(2):899-901. DOI:10.1016/j.apsb.2022.11.017
Abstract

Copyright © 2014 Editorial Office of Acta Pharmaceutica Sinica