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Lipid nanomaterials-based RNA therapy and cancer treatment
Xingcai Zhang, Luo Hai, Yibo Gao, Guocan Yu, Yingli Sun,
2023, 13(3):903-915. DOI:10.1016/j.apsb.2022.10.004
Abstract
Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
Mengnan Zhao, Rujing Wang, Kunmeng Yang, Yuhong Jiang, Yachen Peng, Yuke Li, Zhen Zhang, Jianxun Ding, Sanjun Shi,
2023, 13(3):916-941. DOI:10.1016/j.apsb.2022.10.019
Abstract
Sodium alginate coating simultaneously increases the biosafety and immunotherapeutic activity of the cationic mRNA nanovaccine
Xing Duan, Yi Zhang, Mengran Guo, Na Fan, Kepan Chen, Shugang Qin, Wen Xiao, Qian Zheng, Hai Huang, Xiawei Wei, Yuquan Wei, Xiangrong Song,
2023, 13(3):942-954. DOI:10.1016/j.apsb.2022.08.015
Abstract
Nanoparticles (NPs)-mediated systemic mRNA delivery to reverse trastuzumab resistance for effective breast cancer therapy
Zhihui Dong, Zhuoshan Huang, Senlin Li, Ying Wang, Yandan Yao, Xianzhu Yang, Xiaoding Xu,
2023, 13(3):955-966. DOI:10.1016/j.apsb.2022.09.021
Abstract
Concurrent silencing of TBCE and drug delivery to overcome platinum-based resistance in liver cancer
Senlin Li, Siyu Chen, Zhihui Dong, Xingdong Song, Xiuling Li, Ziqi Huang, Huiru Li, Linzhuo Huang, Ganyuan Zhuang, Ran Lan, Mingyan Guo, Wende Li, Phei Er Saw, Lei Zhang,
2023, 13(3):967-981. DOI:10.1016/j.apsb.2022.03.003
Abstract
Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers
Lei Zhang, Biwei Ye, Zhuo Chen, Zhe-Sheng Chen,
2023, 13(3):982-997. DOI:10.1016/j.apsb.2022.10.002
Abstract
Roles of focal adhesion proteins in skeleton and diseases
Sheng Chen, Tailin He, Yiming Zhong, Mingjue Chen, Qing Yao, Di Chen, Zengwu Shao, Guozhi Xiao,
2023, 13(3):998-1013. DOI:10.1016/j.apsb.2022.09.020
Abstract
Recent advances in bacterial therapeutics based on sense and response
Zhuo Feng, Yuchen Wang, Haiheng Xu, Yunfei Guo, Wen Xia, Chenxuan Zhao, Xiaozhi Zhao, Jinhui Wu,
2023, 13(3):1014-1027. DOI:10.1016/j.apsb.2022.09.015
Abstract
Mitochondrial transplantation as a promising therapy for mitochondrial diseases
Tian-guang Zhang, Chao-yu Miao,
2023, 13(3):1028-1035. DOI:10.1016/j.apsb.2022.10.008
Abstract
Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms
Yanfang Yang, Ke Feng, Liying Yuan, Yuxin Liu, Mengying Zhang, Kaimin Guo, Zequn Yin, Wenjia Wang, Shuiping Zhou, He Sun, Kaijing Yan, Xijun Yan, Xuerui Wang, Yajun Duan, Yunhui Hu, Jihong Han,
2023, 13(3):1036-1052. DOI:10.1016/j.apsb.2022.11.012
Abstract
HBXIP blocks myosin-IIA assembly by phosphorylating and interacting with NMHC-IIA in breast cancer metastasis
Lu Zhang, Xiaolei Zhou, Bowen Liu, Xuhe Shi, Xianmeng Li, Feifei Xu, Xueli Fu, Xue Wang, Kai Ye, Tianzhi Jin, Huimin Sun, Qianqian Li, Weiying Zhang, Lihong Ye,
2023, 13(3):1053-1070. DOI:10.1016/j.apsb.2022.11.025
Abstract
The deubiquitinating enzyme 13 retards non-alcoholic steatohepatitis via blocking inactive rhomboid protein 2-dependent pathway
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Wei Dong, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Jing Feng, Bochu Wang,
2023, 13(3):1071-1092. DOI:10.1016/j.apsb.2022.12.006
Abstract
A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway
Sae-Bom Yoon, Hyowon Hong, Hee-Jong Lim, Ji Hye Choi, Yoon Pyo Choi, Seong Wook Seo, Hyuk Woo Lee, Chong Hak Chae, Woo-Kyu Park, Hyun Young Kim, Daeyoung Jeong, Tran Quang De, Chang-Seon Myung, Heeyeong Cho,
2023, 13(3):1093-1109. DOI:10.1016/j.apsb.2022.12.001
Abstract
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung
Mengyao Hao, Rong Fu, Jun Tai, Zhenhuan Tian, Xia Yuan, Yang Chen, Mingjin Wang, Huimin Jiang, Ming Ji, Fangfang Lai, Nina Xue, Liping Bai, Yizhun Zhu, Xiaoxi Lv, Xiaoguang Chen, Jing Jin,
2023, 13(3):1110-1127. DOI:10.1016/j.apsb.2022.10.006
Abstract
G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes
Xiaoli Wei, Fan Yin, Miaomiao Wu, Qianqian Xie, Xueqin Zhao, Cheng Zhu, Ruiqian Xie, Chongqing Chen, Menghua Liu, Xueying Wang, Ruixue Ren, Guijie Kang, Chenwen Zhu, Jingjing Cong, Hua Wang, Xuefu Wang,
2023, 13(3):1128-1144. DOI:10.1016/j.apsb.2022.10.011
Abstract
Targeting metabolic vulnerability in mitochondria conquers MEK inhibitor resistance in KRAS-mutant lung cancer
Juanjuan Feng, Zhengke Lian, Xinting Xia, Yue Lu, Kewen Hu, Yunpeng Zhang, Yanan Liu, Longmiao Hu, Kun Yuan, Zhenliang Sun, Xiufeng Pang,
2023, 13(3):1145-1163. DOI:10.1016/j.apsb.2022.10.023
Abstract
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice
Xiaoqing Fan, Chutian Mai, Ling Zuo, Jumin Huang, Chun Xie, Zebo Jiang, Runze Li, Xiaojun Yao, Xingxing Fan, Qibiao Wu, Peiyu Yan, Liang Liu, Jianxin Chen, Ying Xie, Elaine Lai-Han Leung,
2023, 13(3):1164-1179. DOI:10.1016/j.apsb.2022.10.016
Abstract
Discovery of novel phosphodiesterase-1 inhibitors for curing vascular dementia: Suppression of neuroinflammation by blocking NF-κB transcription regulation and activating cAMP/CREB axis
Qian Zhou, Meiling Le, Yiyi Yang, Wenjuan Wang, Yuqi Huang, Quan Wang, Yijing Tian, Meiyan Jiang, Yong Rao, Hai-Bin Luo, Yinuo Wu,
2023, 13(3):1180-1191. DOI:10.1016/j.apsb.2022.09.023
Abstract
Development of fluorine-substituted NH2-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability
Xin Jin, Shuai Wang, Limin Zhao, Wenjuan Huang, Yinxiang Zhang, Christophe Pannecouque, Erik De Clercq, Ge Meng, Huri Piao, Fener Chen,
2023, 13(3):1192-1203. DOI:10.1016/j.apsb.2022.08.017
Abstract
Membrane dual-targeting probes: A promising strategy for fluorescence-guided prostate cancer surgery and lymph node metastases detection
Ling-Ling Wu, Qinxin Zhao, Qinghua Wang, Qingyang Zhang, Feiya Yang, Bo Zheng, Hai-Yu Hu, Nianzeng Xing,
2023, 13(3):1204-1215. DOI:10.1016/j.apsb.2022.07.018
Abstract
Discovery of the radio-protecting effect of Ecliptae Herba, its constituents and targeting p53-mediated apoptosis in vitro and in vivo
Jiang Wu, Wenfeng Gou, Zhiyun Wang, Huajie Chang, Deguan Li, Wenbin Hou, Changxiao Liu,
2023, 13(3):1216-1230. DOI:10.1016/j.apsb.2022.09.003
Abstract
The role of phosphatidylcholine 34: 1 in the occurrence, development and treatment of ulcerative colitis
Tengjie Yu, Zhihao Zhou, Shijia Liu, Changjian Li, Zhi-Wei Zhang, Yong Zhang, Wei Jin, Keanqi Liu, Shuying Mao, Lei Zhu, Lin Xie, Guangji Wang, Yan Liang,
2023, 13(3):1231-1245. DOI:10.1016/j.apsb.2022.09.006
Abstract
ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy
Zheng Zhou, Keying Li, Yongchao Chu, Chao Li, Tongyu Zhang, Peixin Liu, Tao Sun, Chen Jiang,
2023, 13(3):1246-1261. DOI:10.1016/j.apsb.2022.09.019
Abstract
Lipid-polymer hybrid nanoparticle with cell-distinct drug release for treatment of stemness-derived resistant tumor
Shiyang Shen, Teng Li, Jinyi Fan, Quanlin Shao, He Dong, Xiao Xu, Ran Mo,
2023, 13(3):1262-1273. DOI:10.1016/j.apsb.2022.11.009
Abstract
An mRNA vaccine elicits STING-dependent antitumor immune responses
Zhe Chen, Chaoyang Meng, Junhua Mai, Yongbin Liu, Hangwen Li, Haifa Shen,
2023, 13(3):1274-1286. DOI:10.1016/j.apsb.2022.11.013
Abstract
Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses
Qunjie Bi, Xu Song, Yangyang Zhao, Xueyi Hu, Huan Yang, Rongrong Jin, Yu Nie,
2023, 13(3):1287-1302. DOI:10.1016/j.apsb.2022.11.004
Abstract
Real-time SERS monitoring anticancer drug release along with SERS/MR imaging for pH-sensitive chemo-phototherapy
Xueqin Huang, Bingbing Sheng, Hemi Tian, Qiuxia Chen, Yingqi Yang, Brian Bui, Jiang Pi, Huaihong Cai, Shanze Chen, Jianglin Zhang, Wei Chen, Haibo Zhou, Pinghua Sun,
2023, 13(3):1303-1317. DOI:10.1016/j.apsb.2022.08.024
Abstract
Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis
Ning Shao, Xueyang Ma, Ying-Ying Zhang, Donghui Yang, Ming Ma, Gong-Li Tang,
2023, 13(3):1318-1325. DOI:10.1016/j.apsb.2022.10.005
Abstract
Rhodojaponin VI indirectly targets Cav2.2 channels via N-ethylmaleimide-sensitive fusion protein to alleviate neuropathic pain
Keliang Chen, Tao Wang, Yong Li, Jun Wu, Cheng-Xiao Zhao, Sheng Liu, Fengrun Sun, Yehong Fang, Jiahuan Hu, Jinping Hu, Chong-Jing Zhang, Haibo Yu, Chao Ma, Shi-Shan Yu,
2023, 13(3):1326-1336. DOI:10.1016/j.apsb.2023.01.021
Abstract
Author correction to “The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway”[Acta Pharm Sin B 12 (2022) 1288-1304]
Geni Ye, Maohua Huang, Yong Li, Jie Ouyang, Minfeng Chen, Qing Weng, Xiaobo Li, Huhu Zeng, Pei Long, Zepei Fan, Junqiang Yin, Wencai Ye, Dongmei Zhang,
2023, 13(3):1337-1339. DOI:10.1016/j.apsb.2022.12.020
Abstract
Author correction to “TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner”[Acta Pharm Sin B 11(12) (2021) 3994-4007]
Huaqing Zheng, Xiaolong Li, Xin Zeng, Chengcui Huang, Mingming Ma, Xiaofei Lv, Yajuan Zhang, Lu Sun, Guanlei Wang, Yanhua Du, Yongyuan Guan,
2023, 13(3):1340-1343. DOI:10.1016/j.apsb.2023.01.001
Abstract

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