column
Cellular nanovesicles for therapeutic immunomodulation: A perspective on engineering strategies and new advances
Endong Zhang, Philana Phan, Zongmin Zhao,
2023, 13(5):1789-1827. DOI:10.1016/j.apsb.2022.08.020
Abstract
Localized delivery of nanomedicine and antibodies for combating COVID-19
Bin Tu, Yanrong Gao, Xinran An, Huiyuan Wang, Yongzhuo Huang,
2023, 13(5):1828-1846. DOI:10.1016/j.apsb.2022.09.011
Abstract
Self-therapeutic metal-based nanoparticles for treating inflammatory diseases
Ruifang Han, Yu Xiao, Qianqian Bai, Chung Hang Jonathan Choi,
2023, 13(5):1847-1865. DOI:10.1016/j.apsb.2022.07.009
Abstract
Polymeric nanocarriers for nose-to-brain drug delivery in neurodegenerative diseases and neurodevelopmental disorders
Rania Awad, Avi Avital, Alejandro Sosnik,
2023, 13(5):1866-1886. DOI:10.1016/j.apsb.2022.07.003
Abstract
Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing
Yub Raj Neupane, Harish K. Handral, Syed Abdullah Alkaff, Wei Heng Chng, Gopalakrishnan Venkatesan, Chenyuan Huang, Choon Keong Lee, Jiong-Wei Wang, Gopu Sriram, Rhonnie Austria Dienzo, Wen Feng Lu, Yusuf Ali, Bertrand Czarny, Giorgia Pastorin,
2023, 13(5):1887-1902. DOI:10.1016/j.apsb.2022.10.022
Abstract
Glycan targeting nanoparticle for photodynamic immunotherapy of melanoma
Yonghyun Choi, Wooic Son, Youngpin Han, Jayoung Chae, Chul-Su Yang, Jonghoon Choi,
2023, 13(5):1903-1918. DOI:10.1016/j.apsb.2022.08.009
Abstract
The traditional Chinese medicines treat chronic heart failure and their main bioactive constituents and mechanisms
Jie Chen, Xiaohong Wei, Qian Zhang, Yuzhuo Wu, Guiyang Xia, Huan Xia, Lingyan Wang, Hongcai Shang, Sheng Lin,
2023, 13(5):1919-1955. DOI:10.1016/j.apsb.2023.02.005
Abstract
The hippo kinases MST1/2 in cardiovascular and metabolic diseases: A promising therapeutic target option for pharmacotherapy
Yunfei Yin, Mingyue Tan, Lianhua Han, Lei Zhang, Yue Zhang, Jun Zhang, Wanqian Pan, Jiaxiang Bai, Tingbo Jiang, Hongxia Li,
2023, 13(5):1956-1975. DOI:10.1016/j.apsb.2023.01.015
Abstract
The dichotomous role of immunoproteasome in cancer: Friend or foe?
Boya Chen, Haiying Zhu, Bo Yang, Ji Cao,
2023, 13(5):1976-1989. DOI:10.1016/j.apsb.2022.11.005
Abstract
Click chemistry and drug delivery: A bird's-eye view
Shameer M. Kondengadan, Shubham Bansal, Ce Yang, Dongning Liu, Zach Fultz, Binghe Wang,
2023, 13(5):1990-2016. DOI:10.1016/j.apsb.2022.10.015
Abstract
Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression
Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kong,
2023, 13(5):2017-2038. DOI:10.1016/j.apsb.2023.03.010
Abstract
The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses
Kan Xing Wu, Thinesshwary Yogarajah, Marcus Wing Choy Loe, Parveen Kaur, Regina Ching Hua Lee, Chee Keng Mok, Yi Hao Wong, Patchara Phuektes, Li Sze Yeo, Vincent T.K. Chow, Yong Wah Tan, Justin Jang Hann Chu,
2023, 13(5):2039-2055. DOI:10.1016/j.apsb.2023.03.015
Abstract
Identification of anti-Mycobacterium tuberculosis agents targeting the interaction of bacterial division proteins FtsZ and SepFe
Hongjuan Zhang, Ying Chen, Yu Zhang, Luyao Qiao, Xiangyin Chi, Yanxing Han, Yuan Lin, Shuyi Si, Jiandong Jiang,
2023, 13(5):2056-2070. DOI:10.1016/j.apsb.2023.01.022
Abstract
Universal chimeric Fcγ receptor T cells with appropriate affinity for IgG1 antibody exhibit optimal antitumor efficacy
Wen Zhu, Yang Wang, Liangyin Lv, Hui Wang, Wenqiang Shi, Zexin Liu, Mingzhe Zhou, Jianwei Zhu, Huili Lu,
2023, 13(5):2071-2085. DOI:10.1016/j.apsb.2023.02.004
Abstract
UHRF1/DNMT1–MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer
Shuye Lin, Hanli Xu, Lin Qin, Mengdi Pang, Ziyu Wang, Meng Gu, Lishu Zhang, Cong Zhao, Xuefeng Hao, Zhiyun Zhang, Weimin Ding, Jianke Ren, Jiaqiang Huang,
2023, 13(5):2086-2106. DOI:10.1016/j.apsb.2023.02.015
Abstract
Enhancement of oligodendrocyte autophagy alleviates white matter injury and cognitive impairment induced by chronic cerebral hypoperfusion in rats
Huiyang Wang, Yueyang Liu, Zhenkun Guo, Minghui Cui, Peng Pang, Jingyu Yang, Chunfu Wu,
2023, 13(5):2107-2123. DOI:10.1016/j.apsb.2023.03.014
Abstract
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury
Duo Xu, Fan Yang, Jiayao Chen, Tianxing Zhu, Fen Wang, Yitai Xiao, Zibin Liang, Lei Bi, Guolong Huang, Zebo Jiang, Hong Shan, Dan Li,
2023, 13(5):2124-2137. DOI:10.1016/j.apsb.2022.12.017
Abstract
Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects
Wei Wei, Qingxuan Zeng, Yan Wang, Xixi Guo, Tianyun Fan, Yinghong Li, Hongbin Deng, Liping Zhao, Xintong Zhang, Yonghua Liu, Yulong Shi, Jingyang Zhu, Xican Ma, Yanxiang Wang, Jiandong Jiang, Danqing Song,
2023, 13(5):2138-2151. DOI:10.1016/j.apsb.2022.12.009
Abstract
8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases
Damijan Knez, Daniel Diez-Iriepa, Mourad Chioua, Andrea Gottinger, Milica Denic, Fabien Chantegreil, Florian Nachon, Xavier Brazzolotto, Anna Skrzypczak-Wiercioch, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Kinga Sałat, Julia Serrano, Ana Patricia Fernández, Aitana Sánchez-García, Ricardo Martínez-Murillo, Claudia Binda, Francisco López-Muñoz, Stanislav Gobec, José Marco-Contelles,
2023, 13(5):2152-2175. DOI:10.1016/j.apsb.2023.01.013
Abstract
Sequential delivery of PD-1/PD-L1 blockade peptide and IDO inhibitor for immunosuppressive microenvironment remodeling via an MMP-2 responsive dual-targeting liposome
Chuan Hu, Yujun Song, Yiwei Zhang, Siqin He, Xueying Liu, Xiaotong Yang, Tao Gong, Yuan Huang, Huile Gao,
2023, 13(5):2176-2187. DOI:10.1016/j.apsb.2023.02.009
Abstract
Data-driven engineering framework with AI algorithm of Ginkgo Folium tablets manufacturing
Lijuan Ma, Jing Zhang, Ling Lin, Tuanjie Wang, Chaofu Ma, Xiaomeng Wang, Mingshuang Li, Yanjiang Qiao, Yongxiang Wang, Guimin Zhang, Zhisheng Wu,
2023, 13(5):2188-2201. DOI:10.1016/j.apsb.2022.08.011
Abstract
Click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries
Huitong Ruan, Yongfang Li, Cheng Wang, Yixu Jiang, Yulong Han, Yiwei Li, Dandan Zheng, Jing Ye, Gang Chen, Guo-yuan Yang, Lianfu Deng, Ming Guo, Xingcai Zhang, Yaohui Tang, Wenguo Cui,
2023, 13(5):2202-2218. DOI:10.1016/j.apsb.2022.06.007
Abstract
Single-shot AAV-vectored vaccine against SARS-CoV-2 with fast and long-lasting immunity
Fuhua Wu, Shuang Luo, Yongshun Zhang, Yangsen Ou, Hairui Wang, Zhaofei Guo, Chunting He, Shuting Bai, Penghui He, Min Jiang, Xiaoyan Chen, Guangsheng Du, Xun Sun,
2023, 13(5):2219-2233. DOI:10.1016/j.apsb.2022.07.004
Abstract
Genomic, transcriptomic, and epigenomic analysis of a medicinal snake, Bungarus multicinctus, to provides insights into the origin of Elapidae neurotoxins
Jiang Xu, Shuai Guo, Xianmei Yin, Mingqian Li, He Su, Xuejiao Liao, Qiushi Li, Liang Le, Shiyu Chen, Baosheng Liao, Haoyu Hu, Juan Lei, Yingjie Zhu, Xiaohui Qiu, Lu Luo, Jun Chen, Ruiyang Cheng, Zhenzhan Chang, Han Zhang, Nicholas Chieh Wu, Yiming Guo, Dianyun Hou, Jin Pei, Jihai Gao, Yan Hua, Zhihai Huang, Shilin Chen,
2023, 13(5):2234-2249. DOI:10.1016/j.apsb.2022.11.015
Abstract
Entinostat, a class I selective histone deacetylase inhibitor, plus exemestane for Chinese patients with hormone receptor-positive advanced breast cancer: A multicenter, randomized, double-blind, placebo-controlled, phase 3 trial
Binghe Xu, Qingyuan Zhang, Xichun Hu, Qing Li, Tao Sun, Wei Li, Quchang Ouyang, Jingfen Wang, Zhongsheng Tong, Min Yan, Huiping Li, Xiaohua Zeng, Changping Shan, Xian Wang, Xi Yan, Jian Zhang, Yue Zhang, Jiani Wang, Liang Zhang, Ying Lin, Jifeng Feng, Qianjun Chen, Jian Huang, Lu Zhang, Lisong Yang, Ying Tian, Hongyan Shang,
2023, 13(5):2250-2258. DOI:10.1016/j.apsb.2023.02.001
Abstract
Berberine improves central memory formation of CD8+ T cells: Implications for design of natural product-based vaccines
Mingyan Li, Yaling Wang, Lingzhi Zhang, Changxing Gao, Jing J. Li, Jiandong Jiang, Qing Zhu,
2023, 13(5):2259-2268. DOI:10.1016/j.apsb.2023.02.017
Abstract
Nimbolide targeting SIRT1 mitigates intervertebral disc degeneration by reprogramming cholesterol metabolism and inhibiting inflammatory signaling
Yun Teng, Yixue Huang, Hao Yu, Cenhao Wu, Qi Yan, Yingjie Wang, Ming Yang, Haifeng Xie, Tianyi Wu, Huilin Yang, Jun Zou,
2023, 13(5):2269-2280. DOI:10.1016/j.apsb.2023.02.018
Abstract
Supramolecular approaches for insulin stabilization without prolonged duration of action
Rolande Meudom, Yanxian Zhang, Michael A. VandenBerg, Lei Zou, Yi Wolf Zhang, Matthew J. Webber, Danny Hung-Chieh Chou,
2023, 13(5):2281-2290. DOI:10.1016/j.apsb.2023.01.007
Abstract
A potentially serious adverse effect of GLP-1 receptor agonists
Jinmiao Lu, Hao Liu, Qingtong Zhou, Ming-Wei Wang, Zhiping Li,
2023, 13(5):2291-2293. DOI:10.1016/j.apsb.2023.02.020
Abstract

Copyright © 2014 Editorial Office of Acta Pharmaceutica Sinica