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Small-molecule agents for cancer immunotherapy
Fang Wang, Kai Fu, Yujue Wang, Can Pan, Xueping Wang, Zeyu Liu, Chuan Yang, Ying Zheng, Xiaopeng Li, Yu Lu, Kenneth Kin Wah To, Chenglai Xia, Jianye Zhang, Zhi Shi, Zeping Hu, Min Huang, Liwu Fu,
2024, 14(3):905-952. DOI:10.1016/j.apsb.2023.12.010
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Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer
Minru Liao, Dahong Yao, Lifeng Wu, Chaodan Luo, Zhiwen Wang, Jin Zhang, Bo Liu,
2024, 14(3):953-1008. DOI:10.1016/j.apsb.2023.12.003
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Epigenetic modification in liver fibrosis: Promising therapeutic direction with significant challenges ahead
Runping Liu, Yajing Li, Qi Zheng, Mingning Ding, Huiping Zhou, Xiaojiaoyang Li,
2024, 14(3):1009-1029. DOI:10.1016/j.apsb.2023.10.023
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Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
Tongyu Huo, Xinyi Zhao, Zengrui Cheng, Jialiang Wei, Minghui Zhu, Xiaodong Dou, Ning Jiao,
2024, 14(3):1030-1076. DOI:10.1016/j.apsb.2023.11.021
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Design consideration of phthalocyanines as sensitizers for enhanced sono-photodynamic combinatorial therapy of cancer
Lindokuhle Cindy Nene, Heidi Abrahamse,
2024, 14(3):1077-1097. DOI:10.1016/j.apsb.2023.11.030
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The role of N-glycosylation in cancer
Yu Lin, David M. Lubman,
2024, 14(3):1098-1110. DOI:10.1016/j.apsb.2023.10.014
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Towards overcoming obstacles of type II photodynamic therapy: Endogenous production of light, photosensitizer, and oxygen
Lin Yu, Zhen Liu, Wei Xu, Kai Jin, Jinliang Liu, Xiaohui Zhu, Yong Zhang, Yihan Wu,
2024, 14(3):1111-1131. DOI:10.1016/j.apsb.2023.11.007
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Metal nanoparticles for cancer therapy: Precision targeting of DNA damage
Qian Chen, Chunyan Fang, Fan Xia, Qiyue Wang, Fangyuan Li, Daishun Ling,
2024, 14(3):1132-1149. DOI:10.1016/j.apsb.2023.08.031
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Development of LAG-3/FGL1 blocking peptide and combination with radiotherapy for cancer immunotherapy
Yuzhen Qian, Yixuan Sun, Peishang Shi, Xiuman Zhou, Qiongqiong Zhang, Qingyu Dong, Shengzhe Jin, Lu Qiu, Xiaoshuang Niu, Xiaowen Zhou, Wenshan Zhao, Yahong Wu, Wenjie Zhai, Yanfeng Gao,
2024, 14(3):1150-1165. DOI:10.1016/j.apsb.2023.12.011
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Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1
Shanshan Rao, Zehui He, Zun Wang, Hao Yin, Xiongke Hu, Yijuan Tan, Tengfei Wan, Hao Zhu, Yi Luo, Xin Wang, Hongming Li, Zhenxing Wang, Xinyue Hu, Chungu Hong, Yiyi Wang, Mingjie Luo, Wei Du, Yuxuan Qian, Siyuan Tang, Hui Xie, Chunyuan Chen,
2024, 14(3):1166-1186. DOI:10.1016/j.apsb.2023.12.009
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EHMT2 promotes tumorigenesis in GNAQ/11-mutant uveal melanoma via ARHGAP29-mediated RhoA pathway
Yongyun Li, Tianyu Zhu, Jie Yang, Qianqian Zhang, Shiqiong Xu, Shengfang Ge, Renbing Jia, Jianming Zhang, Xianqun Fan,
2024, 14(3):1187-1203. DOI:10.1016/j.apsb.2023.12.002
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Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates
Xiaohui Chen, Meichun Gao, Yongzhen Xia, Xin Wang, Jingbo Qin, Hongying He, Weirong Liu, Xiaowei Zhang, Shuangzhou Peng, Zhiping Zeng, Ying Su, Xiaokun Zhang,
2024, 14(3):1204-1221. DOI:10.1016/j.apsb.2023.11.017
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GRK2 mediated degradation of SAV1 initiates hyperplasia of fibroblast-like synoviocytes in rheumatoid arthritis
Paipai Guo, Ji Jiang, Rui Chu, Feng He, Mingli Ge, Ruhong Fang, Qiuyun Guan, Huijuan Cheng, Chunru Jiang, Tiantian Su, Zhenduo Zhu, Hao Liu, Wei Wei, Shihao Zhang, Qingtong Wang,
2024, 14(3):1222-1240. DOI:10.1016/j.apsb.2023.12.007
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Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis
Pengfei Xu, Yue Xi, Jong-Won Kim, Junjie Zhu, Min Zhang, Meishu Xu, Songrong Ren, Da Yang, Xiaochao Ma, Wen Xie,
2024, 14(3):1241-1256. DOI:10.1016/j.apsb.2023.12.006
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Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variants
Zhao Wang, Heng Zhang, Zhen Gao, Zihao Sang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu,
2024, 14(3):1257-1282. DOI:10.1016/j.apsb.2023.11.023
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Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis
Qian Zhao, Jiale Dong, Han Liu, Hui Chen, Huan Yu, Shuyin Ye, Shuangjin Yu, Yu Li, Longhui Qiu, Nazi Song, Hongjiao Xu, Qi Liu, Zhiteng Luo, Yuyi Li, Rui Wang, Guodong Chen, Xianxing Jiang,
2024, 14(3):1283-1301. DOI:10.1016/j.apsb.2023.11.020
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Discovery of a potent and highly selective inhibitor of SIRT6 against pancreatic cancer metastasis in vivo
Xinyuan Xu, Qian Zhang, Xufeng Wang, Jing Jin, Chengwei Wu, Li Feng, Xiuyan Yang, Mingzhu Zhao, Yingyi Chen, Shaoyong Lu, Zhen Zheng, Xiaobing Lan, Yi Wang, Yan Zheng, Xuefeng Lu, Qiufen Zhang, Jian Zhang,
2024, 14(3):1302-1316. DOI:10.1016/j.apsb.2023.11.014
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Mimotope peptide modified pompon mum-like magnetic microparticles for precise recognition, capture and biotransformation analysis of rituximab in biological fluids
Jiawen Yang, Aixuan Zhou, Minyi Li, Qiaoxian He, Jingwei Zhou, Jacques Crommen, Wentao Wang, Zhengjin Jiang, Qiqin Wang,
2024, 14(3):1317-1328. DOI:10.1016/j.apsb.2023.10.018
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Anti-osteosarcoma trimodal synergistic therapy using NiFe-LDH and MXene nanocomposite for enhanced biocompatibility and efficacy
Yani Xu, Lan Yang, Min Li, Haozhou Shu, Na Jia, Yunzhen Gao, Rongying Shi, Xiaojia Yang, Zhirong Zhang, Ling Zhang,
2024, 14(3):1329-1344. DOI:10.1016/j.apsb.2023.10.005
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Biomimetic “Gemini nanoimmunoregulators” orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages
Honglin Huang, Ningxi Li, Xiaodan Wei, Qingzhi Li, Junhan Guo, Geng Yang, Hong Yang, Lulu Cai, Yiyao Liu, Chunhui Wu,
2024, 14(3):1345-1361. DOI:10.1016/j.apsb.2023.11.005
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Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein (RNP) to inhibit herpes simplex virus1 infection in vitro and in vivo
Yuanda Wan, Liren Li, Ruilin Chen, Jiajia Han, Qiyun Lei, Zhipeng Chen, Xiaodong Tang, Wenyu Wu, Shuwen Liu, Xingang Yao,
2024, 14(3):1362-1379. DOI:10.1016/j.apsb.2023.10.004
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Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis
Yixian Li, Peng Yang, Ran Meng, Shuting Xu, Lingling Zhou, Kang Qian, Pengzhen Wang, Yunlong Cheng, Dongyu Sheng, Minjun Xu, Tianying Wang, Jing Wu, Jinxu Cao, Qizhi Zhang,
2024, 14(3):1380-1399. DOI:10.1016/j.apsb.2023.10.009
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The effect of lengths of branched-chain fatty alcohols on the efficacy and safety of docetaxel-prodrug nanoassemblies
Shuo Wang, Tian Liu, Yuetong Huang, Chaoying Du, Danping Wang, Xiyan Wang, Qingzhi Lv, Zhonggui He, Yinglei Zhai, Bingjun Sun, Jin Sun,
2024, 14(3):1400-1411. DOI:10.1016/j.apsb.2023.09.017
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Bioorthogonal microglia-inspired mesenchymal stem cell bioengineering system creates livable niches for enhancing ischemic stroke recovery via the hormesis
Jianpei Xu, Yinzhe Sun, Yang You, Yuwen Zhang, Dan Huang, Songlei Zhou, Yipu Liu, Shiqiang Tong, Fenfen Ma, Qingxiang Song, Chengxiang Dai, Suke Li, Jigang Lei, Zhihua Wang, Xiaoling Gao, Jun Chen,
2024, 14(3):1412-1427. DOI:10.1016/j.apsb.2023.11.009
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Photo-induced crosslinked and anti-PD-L1 peptide incorporated liposomes to promote PD-L1 multivalent binding for effective immune checkpoint blockade therapy
Youngjoo Lee, Sukyung Song, Suah Yang, Jinseong Kim, Yujeong Moon, Nayeon Shim, Hong Yeol Yoon, Sehoon Kim, Man Kyu Shim, Kwangmeyung Kim,
2024, 14(3):1428-1440. DOI:10.1016/j.apsb.2023.09.007
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Genome editing of PAR2 through targeted delivery of CRISPR-Cas9 system for alleviating acute lung inflammation via ERK/NLRP3/IL-1β and NO/iNOS signalling
Xin Zhuo, Yue Wu, Xiujuan Fu, Jianbin Li, Yuxin Xiang, Xiaoyu Liang, Canquan Mao, Yuhong Jiang,
2024, 14(3):1441-1456. DOI:10.1016/j.apsb.2023.08.013
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A novel dual serotonin transporter and M-channel inhibitor D01 for antidepression and cognitive improvement
Yaqin Wei, Xiangqing Xu, Qiang Guo, Song Zhao, Yinli Qiu, Dongli Wang, Wenwen Yu, Yani Liu, KeWei Wang,
2024, 14(3):1457-1466. DOI:10.1016/j.apsb.2023.11.024
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High expression of GPR160 in prostate cancer is unrelated to CARTp-mediated signaling pathways
Chenyu Ye, Qingtong Zhou, Shi Lin, Wensheng Yang, Xiaoqing Cai, Yiting Mai, Yanyan Chen, Dehua Yang, Ming-Wei Wang,
2024, 14(3):1467-1471. DOI:10.1016/j.apsb.2023.11.025
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Commentary: Mammokine directs beige adipocytes to reserve energy for milk production in breast
Lina Tang, Jianping Ye,
2024, 14(3):1472-1476. DOI:10.1016/j.apsb.2023.11.031
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Author correction to ‘Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects’ [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151]
Wei Wei, Qingxuan Zeng, Yan Wang, Xixi Guo, Tianyun Fan, Yinghong Li, Hongbin Deng, Liping Zhao, Xintong Zhang, Yonghua Liu, Yulong Shi, Jingyang Zhu, Xican Ma, Yanxiang Wang, Jiandong Jiang, Danqing Song,
2024, 14(3):1477-1477. DOI:10.1016/j.apsb.2023.12.014
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Author correction to “Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors” [Acta Pharmaceutica Sinica B 12 (2022) 4501-4518]
Yuling Mao, Xiudan Wang, Caishun Chen, Qinfu Zhao, Yanfeng Liu, Jinghai Zhang, Siling Wang,
2024, 14(3):1478-1482. DOI:10.1016/j.apsb.2023.08.005
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